Futibatinib in Intrahepatic Cholangiocarcinoma. 2023-01-19. DOI: 10.1056/NEJMdo006868 Save. Permissions ...

Cholangiocarcinoma is a rare type of cancer, with approximately 8,000 people in the United States receiving a diagnosis each year, according to the American Cancer Society. FGFR2 fusions or ...

肝内胆管癌(intrahepatic cholangiocarcinoma, iCCA)的预后不佳，很大原因是由于诊断不够及时造成的，因此iCCA的早期诊断和及早治疗是提高疾病治愈效果的 ...

The “ubiquitous dependency” of cholangiocarcinoma on CDK4/6 activity, Kongpetch said, suggests that the that the CDK4/6-pRB pathway could be a treatable target.

Intrahepatic cholangiocarcinoma (IHCCA), a global health problem, is increasing in incidence and has differing etiologies worldwide. Next-generation sequencing (NGS) is rapidly being incorporated into ...

Results showed that across 3,038 U.S. counties there were 85,909 cholangiocarcinoma cases and 23,902 cholangioscopies performed — an annual mean volume of 2.5 (standard deviation, 7.1 ...

在肝内胆管癌（ICC）治疗领域，化疗免疫治疗（CIT）取得了显著进展，但仍面临着治疗抵抗的挑战。铁死亡是一种细胞死亡形式，与癌症的发生、发展及治疗抵抗密切相关。PCK1作为代谢关键酶，在多种癌症中发挥着重要作用，但其在ICC中的具体作用尚不清楚。

Across the 3 cholangiocarcinoma subtypes, OS of more than 3 years was associated with lower percentages of PD-1+ cells among the CD8+ T cells than those with OS of less than 3 years.

Cholangiocarcinoma, also known as bile duct cancer, is a rare disease. It's a devastating condition incurable at the point ...

Intraductal neoplasms of the bile duct are macroscopically characterized by exophytic or polypoid growth patterns and have a favorable prognosis. Although some tumors with a predominantly tubular ...

Cholangiocarcinoma is a relatively rare adenocarcinoma of the bile ducts that is rapidly fatal unless it can be completely resected. In most cases, the tumor is too advanced for resection by the ...