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为探究组织蛋白酶 D(CatD)在院内心脏骤停(IHCA)中的作用,研究人员开展相关研究,发现预骤停 CatD 水平与 IHCA 患者死亡率相关,为预后判断提供新依据。 在医学领域,心脏骤停(CA)是极其危急的状况,尤其是院内心脏骤停(IHCA),患者往往面临极差的预后。
CatD target occupancy was used as a surrogate to predict in vivo CatD inhibition and was calculated using an Emax equation based on in vivo average unbound plasma concentrations (Cp,u) and either ...
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