This news release is available in German. Thanks to a fungus, the medicinal plant ribwort plantain gains a higher concentration of the defensive compound catalpol. Biologists at Bielefeld ...

Catalpol, an iridoid glycoside derived from Rehmanniae Radix, has therapeutic potential in neurologic diseases due to its diverse biological activities.

Catalpol exhibits robust anti‐inflammatory and anti‐oxidant activities, partly by modulating key cellular signalling pathways such as AMPK/NOX4/PI3K/AKT and SIRT5-mediated mechanisms.

The increase in catalpol gives the plant better protection against pests. In the study, the research team worked with arbuscular mycorrhizal fungi. These are known to colonize the roots of land ...