Bisphosphonate-mediated inhibition of osteoclast function seems to decrease bone resorption and inhibit normal bone turnover remodelling. Bone resorption and remodelling play an essential role in ...

Bone health management varies across hospitals for older women with early breast cancer who have inconsistent bone density ...

The objective of this study was to clarify the role of bisphosphonates in the treatment of osteoporosis in patients with prostate adenocarcinoma under androgen deprivation therapy (ADT). The ...

Each bisphosphonate registration trial enrolled 3000 to 7500 patients and was powered for the demonstration of fracture efficacy, whereas the long-term extension studies, with enrollments ranging ...

Bisphosphonate use at baseline was uncommon (2%) but had markedly increased by year 6 (10%). Alendronate was the most common type of bisphosphonate, accounting for more than 90% of use. Users of any ...

Intravenous (IV) bisphosphonates reduce the risk of skeletal-related events in patients with multiple myeloma (MM). However, data describing racial differences in IV bisphosphonate utilization outside ...

After adjustment for these factors, bisphosphonate use was associated with an OR of 49.7 (95% CI, 15.9 - 155.1; P < .001) for an atypical fracture.

Rinsing morcellized bone grafts with a bisphosphonate before implantation appears to help prevent graft resorption following revision total hip replacement. It may also reduce the risk for ...

Mavrokokki A, Cheng A, Stein B, et al. The nature and incidence of bisphosphonate associated osteonecrosis of the jaws in Australia. J Oral Maxillofac Surg. 2007;65:415-423.

DEAR PEOPLE’S PHARMACY: I have been taking prednisone since 2008 for an autoimmune disease, and I may spend the rest of my life coping with the adverse effects. The major problem now appears to be ...

Correspondence Atypical Femoral Fractures and Bisphosphonate Use Published May 13, 2010 N Engl J Med 2010;362: 1848 - 1849 DOI: 10.1056/NEJMc0910389 ...

Endocrinology > Osteoporosis Could NSAIDs Negate Bisphosphonate Benefits? — Women taking clodronate and NSAIDs didn't see a protective effect by Kristen Monaco, Staff Writer, MedPage Today April ...