The team of researchers from the Institute of Science Tokyo has discovered that basophils, immune cells that are present in ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Given that human basophils express CLEC12A, a protein that is also highly expressed on the surface of pre-basophils in mice, it seems likely that there is a human counterpart of mouse pre-basophils.

Basophils initiate T helper type 2 responses after exposure to allergens and IgE immune complexes. Juan Rivera and his colleagues find that elevated amounts of IgE in Lyn−/− mice drive ...

"Basophils broadly interact with other cell types of the lung, especially macrophages. Molecular signals, emitted by basophils, assist in the maturation of macrophages into their lung -specific ...

Basophils are a type of white blood cell (leukocyte) classified under granulocytes. They are very rare cells that represent only 0.5% of circulating leukocytes.

Basophils start life in the bone marrow,3 as with many immune cells, as hematopoietic stem cells that are able to differentiate into numerous cell types. To form a basophil, these stem cells must ...

Basophils have long been suspected to be potent inducers of T helper type 2 differentiation. Sokol and colleagues now demonstrate that basophils are required for adoption of the T helper type 2 ...