DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Torino is a computational workflow that uses biobank-scale RNA-seq data to decode transcript structures and expression levels from read coverage alone.

Genetics is the study of genes and how they influence characteristics and health. Through a variety of technological methods, environmental factors, and lifestyle choices, it is possible to alter some ...

A novel, validated seven-gene transcriptomic signature can predict TNF inhibitor response in patients with rheumatoid ...

Engineers have created DIAL, a modular system that precisely sets and edits protein levels in synthetic gene circuits. By ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

MIT engineers develop a new system for precise control of synthetic gene expression, potentially advancing gene therapy.