In the panvascular system, hypoxia-inducible factors (HIFs) can lead to excessive activity of vascular smooth muscle cells (VSMCs), presenting a phenotype of proliferation and migration in ...

They showed that treatment of senescent human vascular smooth muscle cells (VSMCs) with 2-bromopalmitate (2-BP) - an ...

A recent study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

The study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of ...

ScRNA-seq analysis revealed that PDFGRβ+ cells encompassed pericytes/vSMCs and fibroblasts, with the fibroblasts transforming into myofibroblasts after SCI. The team employed Col1a2-CreER::R26 ...

Vascular Smooth Muscle Cells (VSMCs) are also responsible for regulating blood pressure and vascular tone. VSMC proliferation is lowered by reducing EFK phosphorylation and interrupting the G0/G1 ...

他们发现，用2-溴铝酸盐(2-BP)——一种蛋白质酰基转移酶抑制剂——处理衰老的人类血管平滑肌细胞(VSMCs)与衰老表型的不同方面的变化有关，包括细胞增殖的恢复，DNA损伤标记物的减少和衰老 ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...