Around 45 percent of human DNA is made up of transposable elements, or TEs—genetic leftovers from now-extinct viruses that ...

Cells use a range of increasingly well understood epigenetic mechanisms to keep transposable elements under control. These silencing mechanisms have been co-opted during the course of evolution to ...

作为一种关键的研究领域，转座因子（transposable element，也称为转座子）是可以改变在基因组中的位置产生或逆转突变，从而改变细胞的遗传特性的 ...

One person's junk is another's treasure. An international team of scientists have found that strings of "junk" DNA that were ...

Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-15520-5 ...

Transposable elements have been co-opted for new purposes through evolutionary history—for instance, the RAG genes in immune cells and the genes required for driving the development of the ...

Transposable elements reveal a stem cell specific class of long noncoding RNAs Date: November 26, 2012 Source: BioMed Central Limited Summary: Over a decade after sequencing the human genome, it ...

In healthy cells, transposable elements (TEs) are typically inactivated by methylation. But in cancer cells, these elements can become demethylated, enabling them to be expressed (1). Some ...

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection. The findings in ...

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against ...