来自Science的最新研究显示，Ely等研究者通过翻译信息过滤策略，在胰腺癌中发现了一类免疫原性且癌症特异性的非经典HLA-I结合肽（ncHLAp）。这些隐匿抗原源自未注释的开放阅读框（ORFs），研究团队进一步验证了能靶向胰腺导管腺癌（PDAC）的抗原特异性T细胞受体（TCRs），为免疫治疗提供了突破性新靶点。

David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...

A new AI tool that models how variations in peptides change T cell receptor binding could help design immunotherapies with ...

Imagine your immune cells could be modified to attack any kind of cancer. T cell receptor (TCR) therapy has the potential to ...

Consider how immune cells may be tailored to combat any type of cancer. T cell receptor (TCR) therapy has the potential to ...

The Tennessee Consolidated Retirement System (TCRS), which manages a retirement plan for public employees statewide, was the largest institutional shareholder in the U.S.-based iShares MSCI Turkey ...