Subependymal giant cell astrocytoma is a benign brain tumor mostly associated with tuberous sclerosis complex. However, it may be misinterpreted as other high-grade brain tumors due to the ...

Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis Krueger DA, Care MM, Holland K, et al. N Engl J Med. 2010;363:1801-1811 ...

At 17 it is detected by neuroimaging studies ventricular subependymal Astrocytoma. She was treated with everolimus.After six months of treatment, the patient showed clinical and radiological response ...

Background: Subependymal giant-cell astrocytomas (SEGA) are slow growing non-cancerous tumors that can occur in patients with tuberous sclerosis complex (TSC). The objectives of this study were to ...

Tuberous Sclerosis (TS): T1-weighted with gadolinium axial MRI. Note the large, enhancing subependymal nodule on the right. This is a giant tuber in a patient with TS. TS is a multisystemic genetic ...

Tuberous Sclerosis (TS): T1-weighted with gadolinium axial MRIs. Note the numerous small enhancing lesions, most of which are subependymal near the ventricles. This is the typical appearance of ...

The FDA today approved a pediatric dosage form of everolimus to treat subependymal giant cell astrocytoma. It is the first approved pediatric-specific dosage form developed for the treatment of a ...

In this artist's representation of the adult subependymal neurogenic niche (viewed from underneath the ependyma), electrical signals generated by the ChAT+ neuron give rise to newborn migrating ...

There are three types of brain tumors that are often reported in tuberous sclerosis, which include cortical tubers on the surface of the brain, subependymal nodules (SEN) in the walls of ...