Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat ...

A group of Australian scientists has uncovered a new way to fight some of the toughest cancers by targeting an overlooked ...

A WEHI-led study reveals that blocking minor splicing – an RNA process critical for cell division – reduces tumour growth in ...

Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat ...

Pre-mRNA splicing is a fundamental step in mRNA maturation and its discovery in 1977 revolutionized our understanding of gene expression. This collection includes reviews and research articles ...

Alternative splicing has been proposed as a key contributor to the genetic diversity observed in prostate tumors. Here, the authors focus on the clinically relevant consequences of alternative ...

To carry out RNA splicing, cells use the spliceosomal complex, a multiprotein cellular machinery that coordinates the production of mature RNA molecules. RNA splicing is one of the important ways by ...

Splicing has a key role in oncogenesis, tumor suppression, and metastasis in cancer-related genes. Various types of cancers have been linked to changes in alternative splicing.

Alzheimer’s disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment. Nature Aging, 2022; DOI: 10.1038/s43587-022-00290-0 ...

The new, multi-year collaboration will explore modulating RNA splicing to develop potential first-in-class therapies that would direct the immune system to target cancer cells and help more ...

His company, the Chiron Corporation, contributed important scientific discoveries toward treatments for H.I.V., hepatitis B, ...