A genetic postmortem analysis of the brains of patients with schizophrenia suggests dysfunction of dopamine receptors in the caudate nucleus may cause the disorder. Investigators identified a ...

In this meta-analysis, Howes and colleagues studied the nature of dopaminergic dysfunction in schizophrenia. Data were gathered in vivo in 618 patients with schizophrenia and 606 controls using PET or ...

Dopamine, a key neurotransmitter in the brain, plays a vital role in regulating movement, emotion, and cognition. It is central to the pathology of several major neurological and psychiatric ...

You can boost these chemicals through diet, dance, and more.

A novel drug, evenamide, quieted overactive brain circuits in an animal model of schizophrenia, improving memory, social interaction, and dopamine balance, offering hope for tackling symptoms that ...

People with cannabis use disorder (CUD) have higher dopamine levels in an area of the brain linked to psychosis, found a new study published in JAMA Psychiatry. The findings may help explain why ...

Our approach to treating schizophrenia has changed little for more than half a century. But a shift may be underway, emphasizing novel approaches to the disease and its underlying pathology. This ...

Recent studies have examined the relationship between the drug and psychoses and looked at how the brain responds to the substance Lillian Ali - Staff Contributor Researchers found the contribution of ...

Karuna Therapeutics and Bristol Myers Squibb are winners of the 2025 Gizmodo Science Fair for their research and development of Cobenfy (xanomeline-trospium), the first truly novel medication for ...

Schizophrenia and bipolar I disorder are two conditions that have many differences between them. A class of medicines called antipsychotics can be used to treat both conditions but may cause unwanted ...