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MD/PhD student Nick Salgia is first author on a paper in Cancer Cell that helps explain why a rare and hyper-aggressive ...
Sarcomatoid mesothelioma, a histological subtype of malignant pleural mesothelioma, is a very aggressive tumor with a poor prognosis. Histological diagnosis of sarcomatoid mesothelioma largely ...
A study led by Roswell Park Comprehensive Cancer Center helps explain why a rare and hyper-aggressive subtype of kidney ...
Patients who had mRCC with sarcomatoid features in the primary tumor and who were treated with VEGF-targeted therapy were retrospectively identified. Pathology slides were reviewed to determine the ...
Of the 709 patients included in the analysis, 86% had clear cell histology, 7% had papillary histology, 1% had chromophobe histology, and 6% were unclassified. A total of 105 patients received ...
After standard therapy failed, Thomas Bland's doctor turned to a form of immunotherapy known as a checkpoint inhibitor. Now, Mr. Bland is the first stage 4 sarcomatoid kidney cancer patient to be ...
Sixty patients received at least 1 dose of either study agent; the majority (65%) were treatment naïve. The ORR for the overall population was 33% and 50% in patients with clear cell RCC with ...
The 3-year cancer-specific survival rate in patients with sarcomatoid differentiation was 30.1% in 2016-2020 and 6.7% in 2010-2015 (P <.0001).
“Sarcomatoid tumors are highly resistant to anti-cancer therapies, and many patients run out of available treatment options. Our findings might have unveiled a druggable ‘Achilles Heel ...
Sarcomatoid-variant carcinoma, which is comprised of an epithelial component as well as a non-epithelial sarcoma component, is generally found in the bladder.