Sarcomatoid mesothelioma, a histological subtype of malignant pleural mesothelioma, is a very aggressive tumor with a poor prognosis. Histological diagnosis of sarcomatoid mesothelioma largely ...

Sixty patients received at least 1 dose of either study agent; the majority (65%) were treatment naïve. The ORR for the overall population was 33% and 50% in patients with clear cell RCC with ...

Patients who had mRCC with sarcomatoid features in the primary tumor and who were treated with VEGF-targeted therapy were retrospectively identified. Pathology slides were reviewed to determine the ...

Of the 709 patients included in the analysis, 86% had clear cell histology, 7% had papillary histology, 1% had chromophobe histology, and 6% were unclassified. A total of 105 patients received ...

“Sarcomatoid tumors are highly resistant to anti-cancer therapies, and many patients run out of available treatment options. Our findings might have unveiled a druggable ‘Achilles Heel ...

Sarcomatoid carcinomas are made up of both carcinoma - cancer of the epithelial tissue, which lines organs - and sarcoma - cancer of connective tissues like bones.

The 3-year cancer-specific survival rate in patients with sarcomatoid differentiation was 30.1% in 2016-2020 and 6.7% in 2010-2015 (P <.0001).

Sarcomatoid-variant carcinoma, which is comprised of an epithelial component as well as a non-epithelial sarcoma component, is generally found in the bladder.

Several factors associated with a diminished response to immune checkpoint inhibitor (ICI) drugs among patients with metastatic clear cell renal cell carcinoma (ccRCC) have been identified. They ...