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Simvastatin 抑制 ILF3 调控 PD-L1 表达,为胃癌免疫治疗 ...
胃癌治疗面临挑战,免疫治疗至关重要。山东大学齐鲁医院研究人员开展关于 Simvastatin 对胃癌细胞作用的研究,发现其可降低血清 ILF3 和 PD-L1 水平,诱导癌细胞铁死亡(Ferroptosis),增强免疫反应,为胃癌免疫联合治疗提供理论依据。
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