本研究针对贝伐珠单抗 (BEV)治疗卵巢癌时出现的耐药性问题，通过构建BEV敏感和耐药的小鼠模型，结合RNA测序和机器学习方法，鉴定出S100B是调控卵巢癌BEV敏感性的关键分子。研究发现S100B通过clathrin介导的内吞作用进入内皮细胞，下调FOXO1表达，促进β-catenin核转位，从而增强血管生成。S100B抑制剂喷 ...

S100B的短暂升高反映了急性神经胶质激活，与POCD的神经炎症假说一致。 脊柱手术中S100B的显著变化可能源于手术创伤导致的脊髓-脑轴炎症扩散。 而NSE和MMSE的阴性结果或与检测时间窗、样本异质性有关。 Limitations 研究样本量小、异质性高，且未涵盖所有手术类型。

此外，S100B和GFAP水平与MoCA-C评定的一般认知功能呈负相关。GFAP水平与NBMT中空间工作记忆 (SWM)呈正相关，BDNF水平与NBMT中SWM和物体识别记忆 (ORcM)相关 ...

预警飞机是空中的“千里眼”，由于机载预警系统结构复杂，在世界上有能力研制的国家屈指可数。瑞典拥有自己研制的S100B“百眼巨人”系列早期 ...

S100B testing results showed that the higher the S100B level is, the higher the risk of relapse and death, regardless of the cutoff value. Univariate analysis showed that baseline S100B ≥ 0.15 μg/L is ...

The first report concerning serum S100B as a possible biomarker in MHI was published in 1995. [15] Since then, numerous reports and a meta-analysis, documenting the potential of S100B to safely ...

In 2007, S100B was introduced into emergency department (ED) clinical management routines in Halmstad, Sweden. MHI patients with low (<0.10 mikrogram/L) levels of S100B could be discharged without CT.

S100B is released into the blood stream by astrocytes in the brain when brain injury occurs. The authors investigated whether a specific threshold level of S100B would indicate the absence of ...

S100B is released into the blood stream by astrocytes in the brain when brain injury occurs. The authors investigated whether a specific threshold level of S100B would indicate the absence of ...