Although pyrophosphate imaging has been used and researched for decades, data on its use in differentiating light-chain (AL) amyloidosis from transthyretin (ATTR) amyloidosis started around 2013 ...

Small phosphorylated prenyl metabolites are potent activators of γδ T cells in human peripheral blood, but the molecular mechanism underlying their antigenic potency has remained a mystery. New ...

Alisdair R. Fernie, Albrecht Roscher, R. George Ratcliffe, Nicholas J. Kruger, Fructose 2,6-bisphosphate activates pyrophosphate: fructose-6-phosphate 1-phosphotransferase and increases triose ...

Calcium pyrophosphate deposition (CPDD) disease is characterized by the accumulation of calcium crystals in the cartilage tissues of the joints. The crystal deposits cause inflammation of the ...

Among the many unanswered questions about calcium pyrophosphate deposition — formerly called “pseudogout” — perhaps the most important is whether it causes osteoarthritis, a speaker said ...

Canvax, a European supplier of enzymes, recombinant proteins, and similar products, announced the release of a new inorganic pyrophosphate on Aug. 25, 2022. The new enzyme, isolated from E. coli, is a ...

Pseudogout, in contrast, occurs when calcium pyrophosphate dihydrate crystals form in a joint. Many people will form these crystals throughout their life, including nearly half of those aged over ...

3. Fleisch, H, Russell, RG, Straumann, F. Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis. Nature 1966;212:901-903 ...