Article Open access Published: 19 May 2017 Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides Shaun Stairs, Arif Nikmal, Dejan-Krešimir Bučar, Shao-Liang Zheng, Jack W ...

This study highlights novel genotype-driven metabolic adaptations in PM, laying the groundwork for targeted interventions ...

Pyrimidine derivatives have been used in supramolecular chemistry to construct self-assembled structures, such as molecular machines, sensors, and catalysts. The ability of pyrimidines to form ...

Newark, New Castle, USA, May 15, 2023 (GLOBE NEWSWIRE) -- Growth Plus Reports studied and calculated the size of the global market for pyrimidine Analogues in 2022 and expected it to increase at a ...

This article outlines the biological significance of one of the most important heterocycles, the pyrimidine. An attempt has been made to cover most of the physiologically as well as medicinally ...

Researchers from Yale School of Medicine, along with Helsinki University Hospital and University of Helsinki, have reported data from a study that aimed to assess the effects of a common variant in ...

Background: FF10502 is a synthetic pyrimidine nucleoside similar to gemcitabine (gem) with a sulfur in the pentose ring. FF10502 is a more potent inhibitor of DNA polymerase Beta than gem with ...

They observed that combining pyrimidine biosynthesis inhibitors with antiviral nucleoside analogs synergistically inhibited SARS-CoV-2 infection in vitro and in vivo.

The pyrimidine dimers cause a kink in the DNA backbone, halting transcription and protein synthesis. 6-4 pyrimidine pyrimidone adducts undergo isomerization to their Dewar form upon exposure to ...

Frederick F. Becker, Paula Holton, Mathuros Ruchirawat, Jean-Numa Lapeyre, Perturbation of Maintenance and de novo DNA Methylation in vitro by UVB (280-340 nm)-Induced Pyrimidine Photodimers, ...