Prothrombin gene mutation is diagnosed with a blood test. A sample of your blood is sent to a laboratory and the DNA is analyzed to determine if the mutation is present.

Prothrombin gene mutations are most common among people of European ancestry. Heterozygous mutations affect 2% to 4% of people with this background, according to the National Blood Clot Alliance.

We used a PCR assay to prepare full-length human prothrombin complementary DNA (cDNA) obtained from a human liver cDNA library (Clontech) and cloned this into pcDNA TM 3.1 (+) (Invitrogen) to ...

The prothrombin index was compared with the thrombotest index — similarly calculated (Fig. 2). Again, most patients within the therapeutic range by the prothrombin time had thrombotest indexes ...

A prothrombin time test tells you how long it takes your blood to clot. Learn what it looks for, when you might need one, and what the results mean.

Venous thromboembolism (VTE) is a well-recognized complication of cancer. Laboratory parameters might be useful to assess the VTE risk in patients with cancer. The aim of this study was to investigate ...

A concentrated form of prothrombin complex appears to rapidly and permanently reverse the effects of the novel anticoagulant rivaroxaban, a factor Xa inhibitor. But according to results of a small ...

A comparison has been made of the electrophoretic behavior, chemical composition, aminoterminal sequence, and immunological properties of bovine prothrombin, factor IX (Christmas factor), and factor X ...

About The Study: In this unblinded randomized clinical trial, prothrombin complex concentrate had superior hemostatic efficacy and safety advantages to frozen plasma among patients requiring ...

Medications and their Potential to Cause 'Increase in Prothrombin Level' Developed by - Dr. M. Janani Priya, Pharm D Reviewed by - Dr. M. Sree Mohana Preetha, Pharm D Last Updated on Nov 16, 2023 ...