Polyinosinic-polycytidylic acid (poly IC) is an authentic double-stranded RNA and a potent inducer of type I interferons (IFNs) and downstream molecules involved in the innate immune pathway.

The previous study we published in Hepatology demonstrated that polyinosinic-polycytidylic acid (PolyIC), a TLR3 agonist, could trigger the accumulation, proliferation and activation of CTLs, which ...

Activation of the classical nuclear factor-κB (NF-κB) pathway by tumor necrosis factor (TNF), lipopolysaccharide (LPS), and polyinosinic:polycytidylic acid (pIC) in intestinal epithelial cells ...