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编辑推荐: 本研究首次在加蓬入侵物种黑家鼠 (Rattus rattus)中检测到啮齿类疟原虫Plasmodium yoelii,通过系统筛查527只农村地区捕获的啮齿动物,发现2例阳性样本 (0.38%)。研究采用分子生物学技术结合系统发育分析,证实其与当地原生啮齿动物携带的虫株高度同源,挑战了"啮齿类疟原虫仅限原生宿主"的 ...
编辑推荐: 厦门大学生科院,美国国立卫生研究院的研究人员发表了题为“The Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence”的文章,利用CRISPR-Cas9技术,QTL定位等确定了PyHEUL对疟原虫致病性的重要作用,这将为药物或疟疾疫苗的开发提供新的靶点和思路。
Ana S. Franco, Henrique Silveira, Virgílio E. do Rosário, Plasmodium yoelii: Semiquantitative Analyses of Circumsporozoite Protein Gene Expression during the Sporogonic Development of P. y. yoelii and ...
These results do not support a general role for CD81 during Plasmodium vacuole formation, but rather show that P. yoelii and P. falciparum sporozoites use a specific CD81-dependent pathway to ...
Marked increases in phospholipase B activity were measured in spleen homogenates and sera of CD-1 mice given a primary infection of Plasmodium yoelii. The rise in enzyme activity paralleled ...
The researchers used two well-established non-lethal strains of mouse parasites called Plasmodium yoelii XNL and P. chabaudi AS, and determined that acute MHV68 infection can suppress the anti ...
[The number of TIGIT+CD8+ T cells increases but their cytokine secretion decreases in the lungs of Plasmodium yoelii infected mice]. August 01, 2023 [ MEDLINE Abstract ] « Previous Next » ...
VENLO, Netherlands, April 01, 2025--QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced the launch of the QIAprep&amp Plasmodium Kit and two companion assays to support malaria ...
Citation: Martin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, del Portillo HA (2011) Exosomes from Plasmodium yoelii-Infected Reticulocytes Protect Mice from Lethal Infections.