2005), each expressing a variant of paraoxonase (PON1), an enzyme that processes a variety of substrates. Thiobutyrolactones (TBLs) are normally hydrolyzed by PON1 with very low efficiency.

paraoxonase 1; SAA, serum amyloid A; SR-BI, scavenger receptor type BI. A Kontush is a Senior Research Investigator in and MJ Chapman is Director of the Dyslipoproteinemia and Atherosclerosis ...

Rice (Oryza sativa L.) is a staple food for over half of the world's population, alongside major crops like maize, potatoes, and wheat. While most people are familiar with white and brown rice ...

Atherosclerosis is a chronic disease in which modified lipid derivatives and cell infiltrations are mediated through a complex inflammatory process leading to plaque and tissue build up within the ...

amc.uva.nl Objective: To evaluate the role of the inflammatory biomarkers C-reactive protein (CRP), myeloperoxidase, paraoxonase, secretory phospholipase A2 group IIA (sPLA2), lipoprotein-associated ...

Figure 1: Amplification of complex gene libraries by conventional PCR and emulsion PCR. Figure 2: Ethidium bromide–stained agarose gels reveal the absence of size competition and chimeric ...

Increased mRNA expression for cytochrome P450 7A1, Na +-taurocholate cotransporting polypeptide and paraoxonase 1, no change in mRNA expression for small heterodimer partner and bile salt export pump, ...

Objective To determine whether valproate (VPA) monotherapy influences homocysteine metabolism in patients with epilepsy. Design Systematic review and meta-analysis. Data sources We searched all ...

2 Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark; N.Keiding{at}biostat.ku.dk Correspondence to: Professor N Keiding Department of Biostatistics, University of Copenhagen, ...

Circadian regulation of transcriptional processes has a broad impact on cell metabolism. Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial muscle biopsies in ...

Improvements in medical interventions for people with Down's syndrome have led to a substantial increase in their longevity. Diagnosis and treatment of neurological complications are important in ...

Objective To explore the potential associations between high-density lipoprotein (HDL) levels and inflammasome components in the context of systemic lupus erythematosus (SLE). Methods A ...