Figure 1: Amplification of complex gene libraries by conventional PCR and emulsion PCR. Figure 2: Ethidium bromide–stained agarose gels reveal the absence of size competition and chimeric ...

When generating novel tailor-made proteins, protein engineers routinely apply the principles of 'Darwinian' evolution. However, laboratory evolution of proteins also has the potential to test ...

paraoxonase 1; SAA, serum amyloid A; SR-BI, scavenger receptor type BI. A Kontush is a Senior Research Investigator in and MJ Chapman is Director of the Dyslipoproteinemia and Atherosclerosis ...

1 Institute of Cardio-Cerebrovascular Medicine, Central Hospital of Dalian University of Technology, Dalian, Liaoning, China 2 School of Biomedical Engineering, Faculty of Medicine, Dalian University ...

amc.uva.nl Objective: To evaluate the role of the inflammatory biomarkers C-reactive protein (CRP), myeloperoxidase, paraoxonase, secretory phospholipase A2 group IIA (sPLA2), lipoprotein-associated ...

Circadian regulation of transcriptional processes has a broad impact on cell metabolism. Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial muscle biopsies in ...

Vascular endothelial cells, serving as a barrier between blood and the arterial wall, play a crucial role in the early stages of the development of atherosclerosis, cardiovascular diseases (CVDs), and ...

Increased mRNA expression for cytochrome P450 7A1, Na +-taurocholate cotransporting polypeptide and paraoxonase 1, no change in mRNA expression for small heterodimer partner and bile salt export pump, ...

Atherosclerosis is a chronic disease in which modified lipid derivatives and cell infiltrations are mediated through a complex inflammatory process leading to plaque and tissue build up within the ...

Rice (Oryza sativa L.) is a staple food for over half of the world's population, alongside major crops like maize, potatoes, and wheat. While most people are familiar with white and brown rice ...

I joined the University of Sheffield in 2002 as a Senior Clinical Lecturer in Cardiology and subsequently became Professor of Cardiology in January 2011. I am Clinical Lead for the Cardiovascular ...