Chiari malformation, an anomaly of the posterior cranial fossa, also known as Arnold–Chiari malformation, was described in autopsies by Hans Chiari, an Austrian pathologist, in 1891. He defined four ...

Large oscillations of CSF inflow to the brain appeared about every 20 seconds and were tightly coupled to functional magnetic resonance imaging (fMRI) signals of blood flow and electroencephalogram ...

A study spanning 20 years helps nail down the timing of biomarker changes that occur in the period between normal cognition and a diagnosis of sporadic Alzheimer's disease (AD), something that hasn't ...

The brain floats in a sea of fluid that cushions it against injury, supplies it with nutrients and carries away waste. Disruptions to the normal ebb and flow of the fluid have been linked to ...

Biomarker changes that occur in the period between normal cognition and the diagnosis of sporadic Alzheimer’s disease have not been extensively investigated in longitudinal studies. We conducted a ...

Use of exosome analysis to reveal glioma-specific genetic changes in patient serum. Background: Treatment of leptomeningeal metastasis (LMD) remains challenging due to advanced systemic disease at ...

Why sleep has restorative—or damaging—effects on cognition and brain health has been an enduring mystery in biology. Researchers think cerebrospinal fluid (CSF) may flush toxic waste out, “cleaning” ...