Immunotherapy employs patients' own immune systems to fight cancer, and it has shown itself to be an effective treatment in ...

This AI system can analyze up to one million DNA letters at once, predicting how tiny changes in noncoding regions trigger ...

Scientists once dismissed the theory that traits acquired during life could be inherited, but with new evidence and ...

Another Massachusetts biotech has reached the end of the road. | Another Massachusetts biotech has reached the end of the ...

Knocking down EPIC1 sensitized triple negative breast tumor-bearing mice to immunotherapy with the PD-1 inhibitor pembrolizumab.

To identify noncoding mutations that are associated with functional effects in cancer, Dr. Ideker’s team turned back to TCGA data and carried out a systematic analysis of 930 tumors, integrating ...

Campus News New blood test for noncoding RNA significantly improves cancer detection Assistant Professor of Biomolecular Engineering Daniel Kim and his lab are developing more accurate and powerful ...

"These noncoding RNAs may yield new biomarkers and therapeutic targets for cancer treatment, a potential opportunity for personalized medicine given their cell type-specific expression," added ...

Yet other noncoding RNAs have been linked to sundry neurological conditions, including learning disorder s and autism spectrum disorder. Most lack mechanistic explanations for their contributions to ...

Noncoding mutations contribute to autism risk Date: December 14, 2018 Source: Simons Foundation Summary: A whole-genome sequencing study of nearly 2,000 families has implicated mutations in ...

Review Article Published: 08 November 2012 Interpreting noncoding genetic variation in complex traits and human disease Lucas D Ward & Manolis Kellis Nature Biotechnology 30, 1095–1106 (2012 ...

Clinical Implications of Basic Research A Notch for Noncoding RNA in Melanoma Author: Levi A. Garraway, M.D., Ph.D. Author Info & Affiliations Published May 15, 2014 N Engl J Med 2014;370: 1950 - 1951 ...