资讯

Review Article Published: 08 November 2012 Interpreting noncoding genetic variation in complex traits and human disease Lucas D Ward & Manolis Kellis Nature Biotechnology 30, 1095–1106 (2012 ...
This AI system can analyze up to one million DNA letters at once, predicting how tiny changes in noncoding regions trigger ...
These noncoding variants are often enriched in regulatory regions containing transcription factor binding motifs. This pattern suggests that disrupted TF binding may be a core mechanism driving ...
Additional authors of the study, "Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function," include Bindu L. Raveendra, Supriya Swarnkar, Yosef Avchalumov, Xin-An Liu ...