NADPH（还原型辅酶Ⅱ）是细胞内关键的抗氧化分子，它参与生物体内还原性生物合成以及氧化还原反应，在代谢通路中发挥重要作用。但细胞如何 ...

NADPH氧化酶是一类跨膜氧化还原酶，将电子从膜一侧的NADPH跨膜传递给另一侧的氧分子，生成以超氧阴离子和过氧化氢为主的活性氧类物质（ROS ...

NADH 和 NADPH 系统的分区化避免了代谢冲突：NADH 集中于能量产生，NADPH 专注于合成和抗氧化。 植物通过叶绿体和线粒体的协同，在光照下优先利用光能生成 NADPH，黑暗中切换至 NADH 主导的能量代谢；哺乳动物则通过组织特异性表达不同酶亚型，优化代谢效率。

他们将类囊体跨物种递送到动物体衰老病变的细胞内，之后产生ATP（三磷酸腺苷）和NADPH（还原型辅酶II），为细胞供能，在退行性骨关节炎疾病治疗 ...

NADPH通过调节G6PD活性影响铜死亡敏感性，而铜离子载体（如Elesclomol）可同时诱导铁死亡和二硫键死亡，揭示金属代谢与二硫键应激的复杂关联。 凋亡与自噬的差异 凋亡依赖caspase级联反应，而二硫键死亡不涉及DNA断裂或线粒体膜破裂。

A metabolomics quantification of NADPH production and consumption fluxes in proliferating mammalian cells reveals that, in addition to canonical pathways such as the oxidative pentose phosphate ...

NAD+, NADH as well as NADP+, NADPH have been known to play vital roles in energy metabolism, antioxidation, and reductive biosynthesis. Changes in these systems can be monitored using absorbance ...

Biosensors show the ratio of NADPH to NADP⁺ in real time / Insights into the evolution of the protective function of cells Biological cells have many vital functions in the organism. For example, they ...

Matthew J. Evans, Won-Gyu Choi, Simon Gilroy, Richard J. Morris, A ROS-Assisted Calcium Wave Dependent on the AtRBOHD NADPH Oxidase and TPC1 Cation Channel Propagates the Systemic Response to Salt ...

The active NADPH oxidase complex is a six-protein complex. It has two components in its basic state: a membrane-bound complex embedded in the walls of secondary granules and separate cytosolic ...