Allosteric modulators of GABA A receptors include compounds with a range of activities, such as positive allosteric modulators (PAMs), which increase the response of the receptor to GABA, negative ...

Most modulators currently use inorganic semiconductors or crystals as the electro-optic material, but organic-based polymers have the advantages that they can be fabricated with excellent electro ...

05 Apr 2023 Improved absorption during plasma-dispersion pushes modulators to perform better. Absorption is used to push the modulators to perform better. Research by the University of Southampton’s ...

Selective estrogen-receptor (ER) modulators (SERMs) are synthetic nonsteroidal compounds that switch on and switch off target sites throughout the body. Tamoxifen, the pioneering SERM, blocks estrogen ...

Dewpoint Therapeutics Inc. has described TAR DNA-binding protein 43 (TARDBP; TDP-43) modulators reported to be useful for the treatment of traumatic brain injury, frontotemporal dementia and ...

Several companies are developing γ-secretase modulators (see ARF news story), though only a few have purportedly entered clinical testing. After Bristol Myers Squibb halted development of its ...

Optical modulators play a crucial role in modulating light waves for various applications, including telecommunications, defense, and industrial systems.Pune, Sept. 03, 2024 (GLOBE NEWSWIRE ...

Aldeyra Therapeutics Announces Advancement of New RASP Modulators and Recent Preclinical Data in Obesity at 2024 Investor Roundtable Live Webcast Scheduled to Begin at 8:00 a.m. ET Today ...

Conclusions: Taken together, this is the first report of potent PKM2 novel small-molecule cancer metabolism modulators that show promising anti-cancer therapeutic potential in vivo. The favorable DMPK ...

This study investigated the effects of lanthanides on alkaline phosphatase activity, a model enzyme essential for phosphate metabolism. Reactions were conducted in 96-well microplates using a 0.1 M ...

In the realm of test equipment, there are a number of items that you don’t know you need until you need one. That’s probably the case with the HP11720A pulse modulator. [Tom] acquired t… ...