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生物通
2月
基于Landau-Ginzburg-Wilson理论的α-突触核蛋白聚集机制 ...
研究人员通过结合经典分子动力学方法与Landau-Ginzburg-Wilson理论,创新性地构建了蛋白质相互作用模型。以帕金森病生物标志物α-synuclein为研究对象,采用改进的Abelian Higgs模型哈密顿量描述单链能量,并引入修正的Lennard-Jones势与Debye-Huckel势表征多链相互作用。研究发现,四聚体来源的α-synuclein分子 ...
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