Isothiocyanates, naturally occurring compounds derived from glucosinolate precursors in cruciferous vegetables, have emerged as promising agents in cancer chemoprevention.

Synthesis of N-β-brominated alkenyl isothiocyanates via dehydrogenation of alkyl isothiocyanates Journal: Chemical Communications Published: 2024-06-06 DOI: 10.1039/d4cc01666a Affiliations: 2 ...

"Breast cancer, the second leading cause of cancer deaths in women, can be protected against by eating cruciferous vegetables such as cabbage and near relatives of cabbage such as broccoli and ...

This study demonstrates for the first time that phenethyl isothiocyante (PEITC), a naturally-occurring compound, can selectively deplete mutant p53. The authors also made an intriguing observation ...

Denver, Colo. – Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant ...

Mei-Sie Lee, Oxidative Conversion of Isothiocyanates to Isocyanates by Rat Liver, Environmental Health Perspectives, Vol. 102, Supplement 6: Carcinogenic and Mutagenic N-Substituted Aryl Compounds ...

Cabbage plants defend themselves against herbivores and pathogens by deploying a defensive mechanism called the mustard oil bomb: when the plant tissue is damaged, toxic isothiocyanates are formed and ...

High-Pressure Processing of Broccoli Sprouts: Influence on Bioactivation of Glucosinolates to Isothiocyanates. Journal of Agricultural and Food Chemistry, 2017; DOI: 10.1021/acs.jafc.7b01380 ...

On the other hand, sulfur-containing compounds, such as isothiocyanates and polysulfides, which are found in many vegetables, are known to promote geometrical isomerization of carotenoids (e.g ...

Isothiocyanates react readily with the amino-groups of proteins on human skin and mucosal surfaces. Interestingly, the spicy taste of plants in the Brassicaceae family is due to the irritant ...

Isothiocyanates are known for their protective effects against certain cancers, according to a 2023 review in International Journal of Molecular Sciences.