Isothiocyanates react readily with the amino-groups of proteins on human skin and mucosal surfaces. Interestingly, the spicy taste of plants in the Brassicaceae family is due to the irritant ...

High-Pressure Processing of Broccoli Sprouts: Influence on Bioactivation of Glucosinolates to Isothiocyanates. Journal of Agricultural and Food Chemistry, 2017; DOI: 10.1021/acs.jafc.7b01380 ...

This study demonstrates for the first time that phenethyl isothiocyante (PEITC), a naturally-occurring compound, can selectively deplete mutant p53. The authors also made an intriguing observation ...

Denver, Colo. – Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant ...

Isothiocyanates are known for their protective effects against certain cancers, according to a 2023 review in International Journal of Molecular Sciences.

These cruciferous vegetables, a group that also includes brussels sprouts, kale, and turnips, get their bitter taste from isothiocyanates. These compounds reduce inflammation and deactivate cancer ...

On the other hand, sulfur-containing compounds, such as isothiocyanates and polysulfides, which are found in many vegetables, are known to promote geometrical isomerization of carotenoids (e.g ...

"Breast cancer, the second leading cause of cancer deaths in women, can be protected against by eating cruciferous vegetables such as cabbage and near relatives of cabbage such as broccoli and ...

Still, the work is preliminary. And because the drug is just based off isothiocyanates, which are found in foods, simply eating your vegetables probably won’t be enough to actually fight melanoma.

But for humans, eating isothiocyanates confers health benefits. Studies have shown them to have anti-cancer properties, and anti-neurodegenerative effects against diseases such as Alzheimer’s.