2025年8月10日，北京大学/昌平实验室魏文胜团队在Nature Communications发表研究论文，基于一型与二型内含子的第二步剪接反应，开发了两种全新的体外RNA环化方法：PIET（Permuted Intron-Exon through ...

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intron / introns In some genes, not all of the DNA sequence is used to make protein.

It may be time to rethink certain genetic mutations associated with two devastating neurodegenerative disorders—amyotrophic ...

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The losses of genes or introns from the chloroplast genome are of potential utility as phylogenetic characters. Previous broad surveys of angiosperms, along with sequencing studies in Pisum sativum, ...

Findings This mutation involves the deletion of an adenine in intron 11 that abolishes the canonical splice acceptor site of exon 12 (Perrone et al., 2018). This leads to exon 12 skipping and a ...