Moreover, the cells produced these components in a very similar ratio to that found in an intervertebral disc. The authors concluded that the 10 million cell per mL density presented the best balance ...

In-silico modeling to study intervertebral disc degeneration Intervertebral disc degeneration is defined by a progressive loss of water and structure, and consequently of functionality.

IN 1948 and 1950 Lindblom1 , 2 reported his experience with diskography. In these reports he described a method of direct visualization of normal and pathologic lumbar intervertebral disks by means ...

Degenerative disc disease is very prevalent in older stages of life with approximately 90% of individuals older than 50 years of age having some intervertebral disk degeneration, though it may be ...

Objectives: To observe the prevalence of lumbar intervertebral disc degeneration in elite athletes as compared with published literature of changes seen in non-athletes—that is, normal population.

The intervertebral discs connect the vertebrae and give the spine its mobility. The disc consists of a cartilaginous fibrous ring and a gelatinous core as a buffer.

As the world’s population ages, intervertebral disc degeneration (IDD) has become a major medical issue, causing chronic lower back pain and mobility issues that diminish the quality of life for ...

This painful syndrome is closely linked to degenerative changes that impair the function of the intervertebral disc. Dr. Risbud's lab’s work was the first to show a differential expression of HIF-1 in ...

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-25453-2 ...