Indirubin-3′-monoxime is a derivative of the bis-indole alkaloid indirubin, an active ingredient of a traditional Chinese medical preparation that exhibits anti-inflammatory and anti-leukemic ...

Indirubin, a bis-indole obtained from various natural sources, is responsible for the reported antileukemia activity of a Chinese Medicinal recipe, Danggui Longhui Wan. However, its molecular ...

The structural basis for selectivity and potency has been clarified with the crystallisation of a number of the target protein kinases in complex with indirubin inhibitors. In our hands, indirubins ...

Indirubin, the active ingredient in a traditional Chinese herbal medicine, might offer a new strategy for treating glioblastoma, a deadly form of brain cancer. A new study shows that indirubin ...

Indirubin is derived from the Indigo plant. It is the active ingredient in the Chinese herbal remedy called Dang Gui Long Hui Wan, which is used to treat chronic myeloid leukemia.

Indirubin is derived from the indigo plant. It is the active ingredient in the Chinese herbal remedy called Dang Gui Long Hui Wan, which is used to treat chronic myeloid leukaemia.

Discovery of indirubin-based bifunctional molecule with potent anticancer activity Jan. 8, 2024 ...

Indirubin Derivatives Modulate TGFβ/BMP Signaling at Different Levels and Trigger Ubiquitin-Mediated Depletion of Nonactivated R-Smads. Chemistry & Biology, 2012; 19 (11): 1423 DOI: 10.1016/j ...

Indirubin is derived from the Indigo plant. It is the active ingredient in the Chinese herbal remedy called Dang Gui Long Hui Wan, which is used to treat chronic myeloid leukemia.