CHL at EDD + 700 d correlated with AUC IGF-I and IGFBP-3 (EDD–700 d), but IGFBP-3 was the best predictor (r = 0.47, p = 0.01). Wt and CHL at birth were associated with IGFBP-3 levels in these ...

Insulin-like growth factor binding protein-3 (IGFBP-3) seems to take a lead role in healthy eyesight, according to researchers at the University of Florida (UF), Harvard Medical School, and the ...

这篇综述系统阐述了ADAM28（解整合素金属蛋白酶28）在恶性肿瘤中的多重作用机制，重点探讨其通过切割IGFBP-3、vWF和CTGF等底物，调控肿瘤增殖、转移、耐药及免疫逃逸的分子通路（如PI3K/AKT/mTOR、RAS/MAPK），并论证其作为新型生物标志物和靶向治疗靶点的潜力。

The relationship between IGFR-1 and IGFBP-3 expression and cliniopathological factors was evaluated. Univariate and multivariate analyses were performed to define its prognostic significance. Results: ...

Purpose To establish whether the association between milk intake and prostate cancer operates via the insulinlike growth factor (IGF) pathway (including IGF-I, IGF-II, IGFBP-1, IGFBP-2, and IGFBP-3).

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-32214-2 ...

Patients receive NACT IV on day 1 of each 3 week cycle and receive the IGFBP-2 vaccination on day 14. Study treatment includes 3 vaccinations, evaluations at 1 week and 6 months post vaccine and ...

Our previous studies have shown that insulin-like growth factor binding protein 2 (IGFBP-2) is frequently overexpressed in the highly invasive glioblastoma multiforme (GBM). By using a yeast ...