Hirschsprung's disease is a congenital condition that prevents people, usually newborns and young children, from passing stools. Get insights about the disease, its management and treatment.

在新生儿外科领域，先天性巨结肠（Hirschsprung's disease, HD）始终是困扰医患双方的棘手难题。这种因胚胎期神经嵴细胞（Enteric Neural Crest Cells, ENCC）迁移障碍导致的肠神经系统（Enteric Nervous System, ...

为了解决Hirschsprung病 (HD)延迟诊断（诊断年龄>12个月）在低收入和中等收入国家 (LMIC)的临床负担问题，研究人员在南非约翰内斯堡小儿结直肠中心 (JPCC)开展了一项回顾性研究。主题聚焦延迟诊断对手术次数、并发症及功能结局的影响。结果显示，延迟诊断组需更多手术（中位数4次 vs. 非延迟组3次 ...

Hirschsprung disease is a serious and potentially fatal condition affecting the enteric nervous system and defined by the absence of enteric neurons in the distal bowel. This Review provides an ...

But with Hirschsprung disease, some of those nerve cells are missing, so the intestines do not function properly. Instead, the stool moves as it typically should until it reaches the part of the ...

Hirschsprung’s work paved the way for others describing similar cases, but it took until the mid 1900s before the causes of the disease became more clear. A breakthrough in our understanding of ...

Hirschsprung’s Disease that Lia’s son suffered during his growth and development. One of them is that the child’s digestion becomes sensitive.

A man in China had 12kg of compacted faeces and a large part of his gut removed by surgeons. The patient was suffering from a rare disorder known as Hirschsprung’s disease.

HIRSCHSPRUNG'S disease usually presents as acute or chronic colonic obstruction in infants and children. 1,2 There is defective parasympathetic nerve supply to the rectum or rectosigmoid or ...

In Hirschsprung's disease this contraction always occurred after a five-second delay (Fig. 4, 5 and 7 B) and was usually longer in duration than that seen in normal subjects.