In severe cases of COVID-19, a massive release of the endogenous protein HMGB1 in the lungs may contribute to pulmonary inflammation and tissue damage, according to a review article published ...

HMGB1 levels were similar in all 3 groups, they found. “Our work did not demonstrate the use of HMGB1 as a biomarker in our population,” the investigators said.

HMGB1 is an integral player in liver disease, influencing both inflammatory and fibrotic pathways. Its roles in acute liver injury, chronic conditions, and liver cancer make it a valuable ...

In this webinar Prof. Andersson introduces HMGB1 and its function in the innate immune system to further elucidate all hints and scientific findings explaining HMGB1’s role in COVID-19 disease ...

High Mobility Group Box 1 (HMGB1) HMGB1 is a non-histone DNA-binding protein that regulates transcription inside cells. When released extracellularly, it acts as a signaling molecule. Redox-sensitive ...

Eventually, aging comes for us all — but new evidence suggests that in key ways, it may be a contagious condition. In a provocative new study published in the journal Metabolism, scientists from South ...

Pan and his group have developed a proof-of-concept device capable of detecting HMGB1, a protein implicated in endometriosis development and progression, in menstrual blood with 500% more ...

However, it marks an important leap forward; by understanding HMGB1 and its role in asthma, novel interventions can eventually be trialled. Learn how insomnia may increase asthma risk.

Samples were analyzed by immunofluorescence using the Tissue Microarray technique to determine the percentage of fluorescent cells with cytoplasmic HMGB1 (cHMGB1) expression. Results: The ...

PALO ALTO, Calif., Dec. 15, 2021 (GLOBE NEWSWIRE) -- 180 Life Sciences Corp. (NASDAQ: ATNF) (“180 Life Sciences” or the “Company”), a clinical-stage biotechnology company focused on the ...