The paper is intended to give a survey on the state-of-the-art of extrapolation methods for initial value problems in ordinary differential equation systems. All basic discretizations, which are ...

This recommendation became stronger after the peginesatide (an epoetin alfa biosimilar) incident, when the induction of neutralizing antibodies cross-reacted with endogenous erythropoietin, resulting ...

IBM has developed a technique dubbed “zero-noise extrapolation” that mitigates the noise of quantum computations. It might seem counterintuitive, but by repeating the computation at varying ...

An alternative model for extrapolation The proposed method for extrapolating the risk-free yield curve under Solvency II could have serious consequences for insurers, changing their risk profile and ...

The TOE supports scientific justification for extrapolation across other indications that a share common mechanism of action (MOA). The proposed biosimilar ABP 215 is similar to bevacizumab (BEV) with ...

The Extrapolation Fallacy Even talking about "the media" is beginning to seem absurd. Yet we still do it every day.

The reflection paper and extrapolation The European Medicines Agency (EMA) has published a reflection paper regarding the use of extrapolation when developing medicinal products for paediatric use.