内毒素（Endotoxin）又称脂多糖（LPS），是革兰氏阴性细菌细胞壁中的一种成分。当细菌死亡溶解或采用人工方法破坏细菌细胞后，内毒素被释放到 ...

采用阴离子交换树脂技术作为质粒纯化的原理。 推荐原因： 内毒素低于0.05EU/ug Endotoxin-Free系列设计有**的Endo-EF内毒素去除试剂，有效去除内毒素，避免了长时间的氯化铯超速离心步骤，也不需要冰上孵育30min，内毒素含量远远低于市面上同类产品。 得率高 ...

The endotoxin concentration experimentally chosen was 25 000 U/ml, which caused high endothelial cell loss and marked morphological changes in human corneal grafts. 9 Various endotoxin ...

The maximum allowable endotoxin limit for biological preparations is laid down by regulatory bodies across the world; for example, according to FDA guidelines, the maximum endotoxin limit (EU/mL) for ...

Spectral Medical and partner Vantive are ploughing ahead with an application for the approval of their endotoxic septic shock ...

It has also been shown that endotoxin exposure can damage nerve axons directly or indirectly (9), suggesting that it is an essential factor in the pathogenesis of critical illness polyneuropathy (CIP) ...

Endotoxin-free expression: Lipopolysaccharides, commonly found in the outer membrane of gram-negative bacteria, contribute to endotoxin levels after cell lysis.

Endotoxin tests rely on factor C, a lipopolysaccharide-sensing protease found in horseshoe crab blood. When activated, factor C cleaves and activates another protease.

Recently it has been shown that a lot of other, non-immune cells also have this receptor and can be affected by endotoxins. For instance, there’s some evidence now that endotoxin contamination can ...

Endotoxin assays based on that protein, known as recombinant factor C (rFC), have been sold by the company Lonza since 2003 and by bioMérieux since 2016.

Finding Alternative Endotoxin Tests However, even with these many conservation programs, it is widely accepted that the bleeding of horseshoe crabs is not a sustainable solution for endotoxin testing.