编辑推荐： 本研究针对罕见皮肤恶性肿瘤阴囊外佩吉特病（EMPD）的分子机制不明、误诊率高的问题，通过整合37例全外显子测序和28例转录组数据，结合72例验证队列的多区域测序，首次系统揭示FOXA1-SPDEF-AGR2转录调控轴的核心作用，证实其通过激活黏液腺相关基因（如MUC5AC）驱动肿瘤发生，为EMPD的 ...

本研究针对罕见皮肤恶性肿瘤阴囊外佩吉特病（EMPD）的分子机制不明、误诊率高的问题，通过整合37例全外显子测序和28例转录组数据，结合72例验证队列的多区域测序，首次系统揭示FOXA1-SPDEF-AGR2转录调控轴的核心作用，证实其通过激活黏液腺相关基因（如MUC5AC）驱动肿瘤发生，为EMPD的靶向治疗提供 ...

EMPD's High Speed Unit nabs seven drivers clocked well over the limit in Brakpan and Edenvale, with the fastest recorded at 210km/h.

EMPD members protested a drastic cut in overtime hours, which they claim has significantly impacted their financial stability. Previously, officers worked 60 to 80 hours of overtime per month, but ...

The EMPD said that the owners of the impounded vehicles had until 16 June to reclaim their cars. It said that after the date, all unclaimed cars would be auctioned off, with the proceeds going to ...

Extramammary Paget disease (EMPD) is a rare condition characterized by extreme pruritis and eczematoid-like lesions, most commonly of the skin of the external genitalia. EMPD of the vulva accounts for ...

For more than two years, Schroeder had been coping with an extremely rare, invasive cancer called extramammary Paget's disease (EMPD), which had invaded his scrotum, requiring multiple surgeries ...

The City of Ekurhuleni has condemned the ongoing illegal strike by members of the Ekurhuleni Metropolitan Police Department (EMPD) who are allegedly demanding salary adjustments. The City has ...

Because EMPD is so rare, Voelzke said, most studies of the disease have involved only a relative handful of patients treated at a single hospital, usually in Asia.