Recent evidence highlights the complex interplay between the central nervous system and hepatic drug-metabolising enzymes. In particular, the regulation of liver cytochrome P450 (CYP) enzymes by ...

Inhibiting an enzyme called USP30 in mice protects dopamine-producing neurons, which are typically lost as Parkinson's disease (PD) progresses. The corresponding study was published in Nature ...

Researchers have found evidence that spontaneous eye blink activity, which reflects activity in the dopaminergic system, explains the connection between fitness and cognitive function. This is the ...

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease. The model replicates the dopaminergic system's structure ...