Dopamine, a key neurotransmitter in the brain, plays a vital role in regulating movement, emotion, and cognition. It is central to the pathology of several major neurological and psychiatric ...

An overview of how genetics associated with schizophrenia and bipolar can influence how cells communicate, ultimately ...

In this meta-analysis, Howes and colleagues studied the nature of dopaminergic dysfunction in schizophrenia. Data were gathered in vivo in 618 patients with schizophrenia and 606 controls using PET or ...

A genetic postmortem analysis of the brains of patients with schizophrenia suggests dysfunction of dopamine receptors in the caudate nucleus may cause the disorder. Investigators identified a ...

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person's risk of the ...

A McGill University-led study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with psychosis. “This could help explain why cannabis use ...

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person’s risk of the ...

Prof. Alex Nord, right and graduate student Tracy Warren have discovered genetic variants linked to some symptoms of schizophrenia that are currently hard to treat. The work could lead to new insights ...