Psychopharmacological studies in humans suggest important roles for dopamine (DA) D2 receptors in human executive functions, such as cognitive planning and spatial working memory (SWM). However, ...

Dopamine, a key neurotransmitter in the brain, plays a vital role in regulating movement, emotion, and cognition. It is central to the pathology of several major neurological and psychiatric ...

Blocking dopamine receptors in different regions of the amygdala reduces drug seeking and taking behavior with varying longevity, according to research in rats published in eNeuro. The amygdala ...

A new study published in Brain Sciences provides evidence that dopamine promotes movement by directly altering the excitability of key neurons in the brain’s motor circuitry. The research identifies a ...

In the late 1950s, dopamine was recognized as a neurotransmitter in its own right. A specific functional role for dopamine was suggested by the demonstration of its uncharacteristic distribution in ...

Scientists have discovered the key cellular mechanism that underlies the antipsychotic-induced parkinsonism -- which includes involuntary movements, tremors and other severe physical conditions. These ...

Three research hospitals in the Republic of Korea are reporting that restless leg syndrome was associated with an increased ...

A new study reveals a causal link between dopamine and human reward response to music listening. Researchers pharmacologically manipulated dopaminergic transmission of 27 participants while listening ...

Geneva, Switzerland, August 27, 2020 – Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage pharmaceutical company pioneering allosteric modulation-based drug discovery and development, ...