Surgery is currently the first-line treatment for Cushing disease; however, studies of dopamine agonists have demonstrated effective control of cortisol secretion in patients with Cushing disease.

Bromocriptine is unique in that it does not have a specific receptor that mediates its action on glucose and lipid metabolism. Rather, its effects are mediated via resetting of dopaminergic and ...

In a recent study by Paolo Barone and colleagues, a dopamine agonist, pramipexole, improved depressive symptoms after 12 weeks in European and South African patients undergoing antiparkinsonian ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

KarXT, a novel schizophrenia drug, is on the verge of FDA approval, promising to revolutionize treatment. However, access ...

“我们已经在DDS的基础上确定了一个机制。我们发现，在帕金森病的实验模型中，左旋多巴治疗导致位于大脑奖励系统中的一组特定神经元的异常激活，这些神经元与成瘾物质的影响有关。”神经科学系教授、该研究的主要作者Gilberto Fisone解释说。

Here is your chance to improve your child's outlook for the new school term by promoting motivation and perseverance for a ...

The FDA is poised to issue a decision soon on KarXT, a potential first-in-class antipsychotic for schizophrenia. What should ...

This is the cruel paradox of Crystal Methamphetamine, commonly known as ICE. It promises boundless energy and clarity but ...

Dopamine, often referred to as the “feel-good” neurotransmitter, plays a vital role in maintaining motivation, focus, and ...

Scientists had previously identified the functions of two distinct pathways and types of dopamine receptors in the forebrain: the D1 receptors, which activate neurons, and the D2 receptors ...

This is an important behavioral, pharmacological intervention study of the effects of the catecholamine reuptake inhibitor methylphenidate (MPH) on value-based decision-making using a combination of ...