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*仅供医学专业人士阅读参考乳腺癌HER2表达水平区分迎无创评估新模型乳腺癌是全球女性最常见的恶性肿瘤,也是癌症相关死亡的主要原因之一[1]。人表皮生长因子受体2(HER2)在乳腺癌分子分型及治疗中具有关键作用。随着新型抗体偶联药物(ADC)的出现,H ...
他们聚焦于乳腺动态对比增强磁共振成像(DCE-MRI)的图像配准问题,通过分析不同时间点的 MRI 图像,来观察乳腺恶性肿瘤的生长变化。 该项研究成果发表在《Biomedical Signal Processing and Control》杂志上,为乳腺癌的研究开辟了新的方向。
Four dose levels were administered (5 mg/m 2, 8.4 mg/m 2, 16.5 mg/m 2, and 27.5 mg/m 2. Results: 10 patients underwent DCE-MRI scans and eight patients with 44 total evaluable lesions had available ...
*仅供医学专业人士阅读参考常规MRI联合病理数据有望区分乳腺癌HER2三种表达状态,助力治疗决策优化。乳腺癌是我国女性最常见的恶性肿瘤之一,随着分子分型技术的不断发展,人表皮生长因子受体(HER2)的表达状态在乳腺癌的诊疗决策及预后评估中发挥着重要作用[1]。目前,HER2状态主要依赖免疫组化(IHC)和荧光原位杂交(F ...
编辑推荐: 本研究针对胶质母细胞瘤 (GBM)患者放化疗 (RCT)后真性进展 (PD)与假性进展 (PsP)的临床鉴别难题,创新性采用Golden Angle Radial Sparse Parallel动态增强磁共振 (GRASP DCE-MRI)联合动态磁敏感对比 (DSC-MRI)技术,通过83例患者的多参数分析发现:联合Ktrans 、Ve 、Vp 和rCBV参数可将早期鉴别准确率 ...
The DCE-MRI data were analyzed on a voxelby-voxel basis by using a pharmacokinetic model recommended for analysis of clinical DCE-MRI series. Parametric DCE-MR images were compared with tumor blood ...
In this study, DCE-MRI every 6 months "performed well for early detection of invasive breast cancer in high-risk women, accomplishing the ultimate goal of breast cancer screening -- detecting node ...
Methods: Since 2005, 50 subjects with NM-HNSCC (minimum 1 cm) treated with concurrent platinum based chemoradiotherapy were prospectively enrolled and evaluated with DCE-MRI to evalute nodal perfusion ...
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