Aziridine-containing cyclic tetrapeptides possess great potential for covalent protein labeling and can be valuable in screening libraries. Chung et al. describe the synthesis, cyclization, and ...

March 24, 2008 1 min read A version of this story appeared in Volume 86, Issue 12 ...

Elucidation of the cyclization mechanism catalyzed by terpene synthases is important for the rational engineering of terpene cyclases. We developed a chemoenzymatic method for the synthesis of ...