Clozapine is described as the gold standard treatment for schizophrenia but a new cohort study suggests it is associated with an increased risk of infections, particularly in older patients, further ...

Clozapine (CLZ) is a "gold standard" drug for managing treatment-resistant schizophrenia (TRS), who do not respond adequately to first-line antipsychotics. Despite its efficacy with TRS, the use of ...

Clozapine 12.5mg, 25mg, 100mg, 150mg, 200mg; contains phenylalanine. Caution with drugs that affect or are affected by CYPA1A2, 2D6, 3A4. Concomitant strong CYP1A2 inhibitors (eg, fluvoxamine, ...

Three distinct symptoms characterized schizophrenia: positive, negative, and cognitive. Positive symptoms (delusions and hallucinations) improve with typical or atypical antipsychotic medications.