此前，来自 多伦多大学的研究团队 却颠覆性地发现， 常见益生菌之一的乳杆菌能将膳食中的色氨酸代谢为吲哚，增加肿瘤相关巨噬细胞的活性，从而抑制肿瘤免疫，促进胰腺导管腺肿瘤的生长。 该研究发表在Cell子刊 Immunity 上。

After a person quits smoking, an important consideration is how quickly the induction of CYP1A2 dissipates. The primary pharmacokinetic interactions with smoking occur with drugs that are CYP1A2 ...

在忙碌的工作日里，咖啡和奶茶无疑是我们常见的精神慰藉。然而，你有没有想过，为什么有时喝了咖啡依然感到困倦，而奶茶虽甜却可能让人更加焦虑？

The FDA warned that fezolinetant (Veozah), a hormone-free pill for moderate to severe hot flashes caused by menopause, could ...

Figure 1 lists the pharmacokinetic drug interactions with smoking. The most clinically significant interactions appear in the shaded rows and are discussed below.

While the FDA will take into consideration the committee’s vote, the vote is not binding upon the agency. The FDA will make the final decision and has assigned a Prescription Drug User Fee Act (PDUFA) ...

Studies show caffeine response may be partly due to gene variations in the genes CYP1A2 and ADORA2A, which are thought to indicate how slowly or quickly someone can metabolize caffeine.

Dr Grimaldi says if you carry the genetic variation CYP1A2 (AA), for example, you will “almost certainly” metabolise caffeine faster than someone who doesn’t, and therefore feel its effects ...

Analysis compares results from confirmatory trial COBALT in PBC with real-world data from a pre-specified external control group utilizing the ...

May be potentiated by systemic CYP3A4 inhibitors, dual CYP3A4/CYP1A2 inhibitors (eg, erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine); consider risks vs benefits prior to concomitant ...