Despite extensive use of biomarkers in research studies, most Alzheimer’s disease diagnoses in the United States are determined by clinical examination. That may be about to change. The Food and Drug ...

The levels of neuron specific enolase in the cerebrospinal fluid of people with vascular dementia appeared to be approximately 70 percent those of people with Alzheimer's disease (effect size = 0.709, ...

A CSF leak occurs when cerebrospinal fluid (CSF) escapes from the protective layer surrounding the brain and spinal cord. This is a serious condition that can cause headaches, seizures, or ...

Interestingly, Palumbo et al. 2008 [48] showed that CSF NSE level has the same behavior as the other accepted markers of AD, being correlated with Abeta42 and total protein tau (h-tau).

Preterm babies are at risk for mental and developmental retardation. NSE represents the 1.4% of the total soluble protein of the brain. An increase in the CSF level of NSE may indicate neuronal ...