Tregs were defined as CD4 + CD25 hi T cells, and this subset was significantly elevated in the cancer patients compared with normal donors (7.75% v 2.24%). The CD4 + CD25 hi T-cell pool in the ...

The CD4+CD25+ cell subpopulation includes Treg cells that hamper the antileukemic immune response. 49 In our study, the frequency of CD4+CD25+FoxP3+ Treg cells among CD4+ lymphocytes was similar ...

Yanyan Qu, Shuguang Jin, Aijun Zhang, Baojun Zhang, Xiaoyun Shi, Junjie Wang, Yong Zhao, Gamma-Ray Resistance of Regulatory CD4⁺CD25⁺Foxp3⁺ T Cells in Mice ...

A question that has received a great deal of attention in evaluating new treatments in acquired immune deficiency syndrome (AIDS) clinical trials is that of finding a good surrogate marker for ...

Erratum Published: May 2001 Erratum: Thymic selection of CD4 + CD25 + regulatory T cells induced by an agonist self-peptide Nature Immunology 2, 468 (2001) Cite this article ...

Checking CD4 helper T cell levels up to 4 times a year has been a mainstay of HIV /AIDS monitoring, but the value of the test has diminished as the ability to directly detect viral RNA has ...

Traditionally considered as auxiliary cells, CD4 T cells produce molecules to support the action of other immune cells by facilitating their functions, migration or proliferation in the organism ...

Urinary CD4+ T cells can predict renal flares in patients with ANCA-associated vasculitis (AAV) better than current clinical standards, “and therefore potentially serve as a novel biomarker to ...

Preclinical evaluation of IBIO-101, produced with iBio’s FastPharmingand GlycaneeringSMSystems, showed equivalent efficacy and potency compared with this IL-2 sparing anti-CD25 antibody made ...

Between September 2003 and July 2005 57 patients were enrolled in the study with 48 patients available for analysis (45 MM, 12 RCC). Tregs were defined as CD4 + CD25 hi T cells, and this subset was ...